Strand Life Sciences

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The Genomic

Diagnostics Specialists

~20,000 genes, billions of genomic characters, millions of genomic variants, tens of panels, hundreds of steps, new literature emerging at breakneck pace, we have it all covered for you

We spun off from the Indian Institute of Science. We created the first College of American Pathologists-accredited laboratory for Genomic Sequencing in India. We have contributed to ~25000 peer-reviewed scientific publications that push the frontiers of genomics research. The bioinformatics platforms and the medical literature curation capabilities that power our tests are tried and tested, not only by us but by many leading global genomics companies

Oncology Treatment Selection

There are ~55 genomic biomarkers that influence Standard of Care therapeutic decision-making. In addition, there are ~120 genomic biomarkers that influence therapy choice on an experimental basis. Our tests cover all the above, both from tissue and from liquid biopsies. Our reporting is driven by decade long investment in curating medical literature per the Association of Molecular Pathology Guidelines. Here is a publication showing the extensive validation our tests goes through.

Breast Cancer

Ovarian Cancer

Lung Cancer

Colon Cancer

Prostate Cancer

Endometrial Cancer

All Cancers

Cancer Risk

~10% of all breast and ovarian cancers globally and a fraction of colorectal, prostate and pancreatic cancers occur on account of inherited mutations. Our pioneering publication shows this fraction is at least as high if not substantially higher in India.

Rare Diseases and Reproductive Health

Our Exome and Low Pass Whole Genome tests along with supporting Sanger/MLPA tests provide a comprehensive solution to the diagnosis of ~5000 Mendelian diseases. Our tests ensure accurate calling of Single Nucleotide Variants, Insertions, and Deletions, as well as Multi-exon and some single-exon Deletions & Duplications to achieve industry-leading diagnostic rates.

In a cohort of >1000 Pediatric Neurology cases, 12% of the variants called by our test were copy number variants that are otherwise hard to identify (see publication)

GenomicWellness

For healthy adults who are curious about their genomes: get your genome sequenced and keep in touch with the scientific progress that is happening at a breakneck pace to manage any genomic risks to your health.

Genomic Health Insights

For those who are curious about their genome: get your genes sequenced and keep in touch with scientific progress that can help manage any genomic risks to your health. We will sequence all ~20,000 genes and you will receive your results on a secure portal comprising risk reports for various diseases, carrier status for mutations that might affect your children, as well as genetic predispositions to commonly used drugs.

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Breast Assure - Strand's HBOC Test

Hereditary Breast and Ovarian Cancer syndrome (HBOC) is a genetic condition that makes it more likely that a person will get breast, ovarian, and other cancers.

HBOC is hereditary, meaning that it is caused by a mutation (genetic change) that can be passed down in families. A genetic test can help determine if your personal or family history of cancer was caused by HBOC. If you are found to have HBOC, there are interventions that can help prevent cancer or detect it early.

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Bioinformatics & Variant Interpretation

Genome sequencing on a single sample yields 10-100 Gigabytes of data; it’s easy to miss the important bits unless ones analytical platforms are robust and thorough. Our proprietary platforms below have been built entirely from scratch and have matured over a decade of clinical use.

Strand NGS

Strand NGS processes GBs of data automatically to convert raw sequencing output to genomics variants. Over 800 global publications and industry leading visualization attest to its robustness

Strand Omics

With streamlined workflows, powerful filtering, extensive curated content, and detailed audit logs, Strand Omics enables reliable identification of the one or two key genomic variants from the tens to hundreds of thousands found for each sample in inherited diseases cases.

Strand Iris

With its extensive database of 30,000 variants in 600 genes, ~750 drug associations, 80,000 clinical trials and an extensive rules engine, Strand Iris enables robust and automated identification of appropriate cancer treatment

Covid-19 Genomic Surveillance

Strand is part of the INSACOG consortium and worked closely with philanthrophic partners and the Bangalore municipality to monitor the evolution of SARS-CoV-2 strains in and around Bangalore.

Strand Testing Process

Pre-test session

with certified Genetic Counsellor where relevant

Sample Collection

(Blood, Saliva, Tissue Block)

Logistics

Pan-India coverage with 24-72 hours shipping

Lab Processing

Sample Preparation & Sequencing

Bioinformatics

Variant Interpretation

Reports Signout

Dispatched by email or accessed secure portal

Post-test session

with certified Genetic Counsellor where relevant

Trusted by Global Companies

What Our Customers Say

“Our child Sireesha had shown signs of developmental delay and poor intake of food from birth. Clinical diagnosis and confirmatory genetic testing revealed a case of Cornelia de Lange Syndrome (CdLS). Genetic testing and counseling has helped us better understand her condition for future treatment.”

Sireesha’s Parents *

“I got a 360 degree view of my cancer profile using the StrandAdvantage 152-gene test, helping me understand my treatment better and be at peace with the probabilities.”

Ila Jindal, 53 *

“Given that we had lost two of our precious children to muscular dystrophy, we wanted to ensure that the current pregnancy would be safe. The Strand test gave us confidence to go ahead with this pregnancy. We are now blessed with a healthy child!”

Radhika and Sundar *

“Genetic testing revealed certain mutations in my genome which could be targeted with precise drugs to eliminate the cancer with minimal side effects.”

Humaira, 57 *