Epigenomics

Explores heritable changes in gene expression that don't involve the DNA sequence itself, such as DNA methylation.
Methylation Sequencing
DNA methylation is an epigenetic mechanism involving the transfer of a methyl group onto the C5 position of the cytosine to form 5-methylcytosine. It regulates gene expression by recruiting proteins that repress the activity of or inhibit the binding of transcription factors to DNA. Methylation usually occurs on the cytosine nucleotides of CpG dinucleotides.
Methylation Sequencing
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Targeted Methylation
Targeted DNA methylation analysis is a molecular biology technique that allows researchers to investigate methylation patterns at specific DNA regions, such as particular genes or genomic loci. Instead of examining the entire genome, this focused approach enables detailed analysis of epigenetic modifications in these targeted areas. This technique is frequently employed in cancer research to identify potential biomarkers based on DNA methylation patterns.
Targeted Methylation
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Methylation Array
A methylation array is a research tool used to measure DNA methylation levels across the genome. By analyzing these chemical modifications (methylation patterns), scientists can study how gene expression is affected, providing insights into various biological processes and diseases.
Methylation Array
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