The MaatriSeq Non-Invasive Prenatal Screening (NIPS) Advance test is a cell-free DNA-based screening method used to detect chromosomal abnormalities in the fetus during pregnancy. This test is an extension of the MaatriSeq NIPS test, and screens for six common microdeletions and duplications, including DiGeorge syndrome (22q11.2 deletion), 1p36 deletion syndrome, Prader-Willi syndrome (15q11.2-q13 deletion), Angelman syndrome (15q11.2-q13 deletion), Cri-du-Chat syndrome (5p15 deletion), and Wolf-Hirschhorn syndrome, along with autosomal and sex chromosomal aneuploidies.
