Strand Clinical Exome Test

  • What information can the Strand Clinical Exome Test provide?
    • The test provides underlying genetic information for more than 3000 inherited disease conditions by analysing genes associated with known clinical phenotypes for presence of mutations.
  • What are the benefits of doing the Strand Clinical Exome Test?
    • The clinical exome test can provide the following benefits:
    • A genetic explanation for disease with complex phenotypes can be established
    • Enables differential diagnosis of diseases
    • Provide comprehensive information on disease subtypes
  • When can the the Strand Clinical Exome Test be ordered?The clinical exome test can be ordered for:
    • Genetic confirmation of a phenotypic diagnosis in affected individuals
    • Carrier testing to identify if parents carry the defective gene responsible for cause of disease
    • Prenatal diagnosis for pregnancy decisions*
  • Turnaround Time
    • The test report is delivered 6-7 weeks from receipt of sample in the lab.
  • Sample requirement (any one of the following)
    • Saliva in collection kits provided by Strand
    • Blood in EDTA tubes (2-5ml)
    • Dry blood spot (in kits provided by Strand)
    • Buccal swab (in kits provided by Strand)
    • DNA isolated from blood



Order Test

ORDER TEST

Strand Inherited Genetic Disorder Test

  • What disorder types are covered under the Strand Inherited Genetic Disorder Test?
    • The Strand Inherited Genetic Disorder Test is offered as sub-panels covering the following disorders:
      • Neuromuscular disorders
      • Neurodevelopmental disorders
      • Neurocognitive disorders
      • Inborn Errors of Metabolism disorders
      • Mitochondrial disorders
      • Neonatal disorders
      • Eye disorders
      • Skeletal disorders
      • Dermatological disorders
      • Cardiac disorders
      • Nephrological disorders
  • What information can the Strand Inherited Genetic Disorder Test provide?
    • The test provides underlying genetic information of complex and heterogeneous disorders enabling accurate and rapid clinical diagnosis.
  • What are the benefits of ordering a Strand Inherited Genetic Disorder Test?
    • The tests can provide the following benefits:
    • Establish a genetic explanation for disease with complex phenotypes.
    • Enable differential diagnosis between syndromic and non-syndromic forms of disorders.
    • Provide comprehensive information on disease subtypes.
  • When can the Strand Inherited Genetic Disorder Tests be ordered?
    • The tests can be ordered for:
    • Genetic confirmation of a phenotypic diagnosis in affected individuals.
    • Carrier testing to identify if parents carry the defective gene responsible for causing a disease.
    • Prenatal diagnosis for pregnancy decisions.*
    • Phenotypically healthy neonates.$
    • Neonates with suspected metabolic, endocrine or immune system disorders, or those who manifest cardiac and hearing problems.
  • Sample requirement (any one of the following)
    • Saliva in collection kits provided by Strand
    • Blood in EDTA tubes (2-5ml)
    • Dry blood spot (in kits provided by Strand)
    • Buccal swab (in kits provided by Strand)
    • DNA isolated from blood

*Prenatal Testing

Prenatal diagnosis is only offered based on the identified mutation in the proband sample or after carrier testing in the parents.

Prenatal test requirements:

  • maternal cell contamination certificate
  • Form F/ G

Sample required : Fetal DNA from CVS or Amniocentesis

$Neonatal testing

Only pathogenic and likely pathogenic variants are reported for risk assessment of healthy neonates with no clinically significant manifestations.