Somatic Homologous Recombination Repair Test (sHRR)

Test Code
SLS162800
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What is the Somatic Homologous Recombination Repair Test?

This test analyzes genes involved in the homologous recombination repair (HRR) pathway, which is an essential mechanism for repairing double-strand DNA breaks. Tumors with deficiencies in this pathway may struggle to repair DNA damage, making them more sensitive to certain therapies, including PARP inhibitors.

Genes Covered/ No. of Genes: 19 Genes

Who Is This Test For?

Patients with cancers such as ovarian, breast, pancreatic, or prostate cancer, where DNA repair mechanisms influence treatment outcomes

Key Features

Evaluates 19 key HRR-related genes in tumor tissues

Clinical Applications

  • Identifies eligibility for DNA-damaging therapies, like PARP inhibitors
  • Provides insights into the tumor’s aggressiveness and potential progression
  • Assists in personalizing treatment plans based on the tumor’s repair capacity
Breast Cancer, Ovarian Cancer, Prostate Cancer, Pancreatic Cancer, Colorectal Cancer, Endometrial Cancer, Gastric Cancer, Biliary Duct Cancer, Lung Cancer

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