Understanding your inherited risk for cancer is the first step in making informed choices—for prevention, early detection, and treatment. But not all genetic changes are easy to detect. This is where a combined approach using Next-Generation Sequencing (NGS) and Digital Multiplex Ligation-dependent Probe Amplification (Digital MLPA) offers significant advantages.
What Is Digital MLPA?
MLPA (Multiplex Ligation-dependent Probe Amplification) is a high-resolution method for detecting CNVs. It enhances what NGS can do, especially in challenging areas of the genome.
Building on conventional MLPA principles, Digital MLPA integrates with NGS platforms for enhanced throughput and resolution.
Why Use Both NGS and Digital MLPA?
Digital MLPA Workflow:
How does Digital MLPA help the patient?
- A more complete genetic risk report
- More confidence in your results
- More tailored care based on accurate data
- Less chance of missing a serious variant
- Only a small blood sample is needed
The integration of NGS and Digital MLPA enhances our ability to detect a broader spectrum of genetic variants, improves the accuracy and reliability of results, and ultimately supports more personalized and informed patient care, ensuring that clinical decisions are backed by comprehensive and high-quality genetic data.