Project:
     Internal R&D Project (Patent pending)
   
Goal:
     Develop a mathematical model of the Liver Homeostasis

Strand’s Solution: 

• Strand has developed a virtual liver model (patent pending) that can
• Reproduce homeostasis (behave like a “normal liver”)
• Quantify the evolution homeostasis to disease and simulate toxicity
• Identify important pathways involved in disease
• Can reproduce cholestasis, necrotic/apoptotic cell death, steatosis
• Evaluate toxicity potential of drug candidates

 Validation:

• Model is validated using reports in literature
• Wet lab validation is in process